Wound, Ostomy and Continence Nurses Society (WOCN) Practice Exam

What is an effect of NPWT on wound bed cells?

1. Increases bacterial colonization

2. Decreases oxygen supply

3. Helps contract and synthesize collagen

4. Promotes necrosis in tissues

The correct answer is: Helps contract and synthesize collagen

The correct answer highlights an essential benefit of Negative Pressure Wound Therapy (NPWT) on wound healing. NPWT creates a controlled environment that encourages the contraction of wound edges and stimulates the activity of fibroblasts, which are crucial cells in the healing process. These fibroblasts contribute to collagen synthesis, leading to improved structural integrity and strength of the new tissue. Through the application of negative pressure, NPWT enhances perfusion and oxygenation within the wound bed, promoting cellular activity and reducing inflammation. This fosters an environment conducive to healing, as collagen is vital for tissue repair and regeneration. As a result, the application of NPWT effectively aids in the formation of granulation tissue and helps accelerate the healing process. In contrast, options related to bacterial colonization, oxygen supply, and necrosis do not align with the benefits provided by NPWT. The therapy is specifically designed to reduce bacterial load and enhance oxygen delivery to tissues, counteracting any notions of promoting necrosis. Overall, option C accurately reflects the positive cellular effects NPWT has on wound healing.