Wound, Ostomy and Continence Nurses Society (WOCN) Practice Exam

What must be maintained to facilitate epithelial cell proliferation during wound healing?

1. Low humidity levels

2. Normal blood glucose levels

3. Presence of necrotic tissue

4. High levels of edema

The correct answer is: Normal blood glucose levels

Maintaining normal blood glucose levels is crucial for facilitating epithelial cell proliferation during the wound healing process. Glucose plays a significant role in cellular metabolism, energy production, and the synthesis of extracellular matrix components. Elevated blood glucose levels can impair immune function, increase the risk of infection, and delay the healing process. Optimal glucose levels ensure that cells have the necessary energy to proliferate, migrate, and carry out their functions effectively during the healing phase. In contrast, low humidity levels can lead to desiccation of the wound site, inhibiting cell migration and proliferation. The presence of necrotic tissue can also impede the healing process, as it can lead to infection and prevent the formation of healthy granulation tissue. High levels of edema may obstruct blood flow and nutrient delivery to the tissue, hindering the healing response. Thus, maintaining normal blood glucose levels is a fundamental aspect of promoting efficient wound healing and epithelial cell proliferation.