Wound, Ostomy and Continence Nurses Society (WOCN) Practice Exam

When does the epithelial cell proliferation and migration phase typically begin?

1. Within 24 hours

2. Within 48 hours

3. Within 8 hours

4. Within 72 hours

The correct answer is: Within 8 hours

The epithelial cell proliferation and migration phase typically begins within 8 hours after injury. This critical phase is part of the wound healing process, where the body regenerates the epithelial layer to protect the underlying tissue and prevent infection. During this initial phase of healing, epithelial cells begin to migrate across the wound bed, covering the area and facilitating the restoration of the skin barrier. This rapid response is essential for reducing risk of infection and promoting further healing processes. The significance of the 8-hour timeframe lies in the body's innate capability to respond quickly to tissue damage, setting the stage for subsequent phases of healing which involve more complex cellular activities. Understanding this timeline helps in assessing wound healing progress and determining appropriate interventions.